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Natural Foxp3(+) regulatory T cells inhibit Th2 polarization but are biased toward suppression of Th17-driven lung inflammation

nTregs prevent autoimmunity and modulate immune and inflammatory responses to foreign antigens. CD4(+)Foxp3(+) nTregs from DO11.10 mice were expanded ex vivo, and their effectiveness in suppressing the development of lung inflammatory responses, elicited by differentiated CD4(+) T cells following an...

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Autors principals: Girtsman, Teri, Jaffar, Zeina, Ferrini, Maria, Shaw, Pamela, Roberts, Kevan
Format: Artigo
Idioma:Inglês
Publicat: The Society for Leukocyte Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924601/
https://ncbi.nlm.nih.gov/pubmed/20495073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0110044
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