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Cutting Edge: Lung mucosal Th17-mediated responses induce polymeric immunoglobulin receptor expression by the airway epithelium and elevate secretory IgA levels

Polymeric immunoglobulin receptor (pIgR) is a central player in mucosal immunity that mediates delivery of polymeric IgA and IgM to the apical surface of epithelial cells via transcytosis. Emerging evidence suggests that Th17 cells, not only mediate autoimmunity, but also play key roles in mucosal h...

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Autori principali: Jaffar, Zeina, Ferrini, Maria E., Herritt, Lou A., Roberts, Kevan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740792/
https://ncbi.nlm.nih.gov/pubmed/19342622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900237
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