A functional polymeric immunoglobulin receptor in chicken (Gallus gallus) indicates ancient role of secretory IgA in mucosal immunity.

Animals are continuously threatened by pathogens entering the body through natural openings. Here we show that in chicken ( Gallus gallus ), secretory IgA (sIgA) protects the epithelia lining these natural cavities. A gene encoding a chicken polymeric Ig receptor ( GG-pIgR ), a key component of sIgA...

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Main Authors: Wieland, Willemien H, Orzáez, Diego, Lammers, Aart, Parmentier, Henk K, Verstegen, Martin W A, Schots, Arjen
格式: Artigo
語言:Inglês
出版: 2004
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224204/
https://ncbi.nlm.nih.gov/pubmed/14992684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040200
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