A functional polymeric immunoglobulin receptor in chicken (Gallus gallus) indicates ancient role of secretory IgA in mucosal immunity.

Animals are continuously threatened by pathogens entering the body through natural openings. Here we show that in chicken ( Gallus gallus ), secretory IgA (sIgA) protects the epithelia lining these natural cavities. A gene encoding a chicken polymeric Ig receptor ( GG-pIgR ), a key component of sIgA...

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Detalhes bibliográficos
Main Authors: Wieland, Willemien H, Orzáez, Diego, Lammers, Aart, Parmentier, Henk K, Verstegen, Martin W A, Schots, Arjen
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224204/
https://ncbi.nlm.nih.gov/pubmed/14992684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040200
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