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Retention of spliceosomal components along ligated exons ensures efficient removal of multiple introns
The majority of mammalian pre-mRNAs contains multiple introns that are excised prior to export and translation. After intron excision, ligated exon intermediates participate in subsequent intron excisions. However, exon ligation generates an exon of increased size, a feature of pre-mRNA splicing tha...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924538/ https://ncbi.nlm.nih.gov/pubmed/20610656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2186510 |
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