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Retention of spliceosomal components along ligated exons ensures efficient removal of multiple introns

The majority of mammalian pre-mRNAs contains multiple introns that are excised prior to export and translation. After intron excision, ligated exon intermediates participate in subsequent intron excisions. However, exon ligation generates an exon of increased size, a feature of pre-mRNA splicing tha...

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Detalhes bibliográficos
Main Authors: Crabb, Tara L., Lam, Bianca J., Hertel, Klemens J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924538/
https://ncbi.nlm.nih.gov/pubmed/20610656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2186510
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