Emulsified Nanoparticles Containing Inactivated Influenza Virus and CpG Oligodeoxynucleotides Critically Influences the Host Immune Responses in Mice

BACKGROUND: Antigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy to elicit a robust and broadened immune response. We assessed the immunogenicity of an inactivated H5N1 whole-virion vac...

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Main Authors: Huang, Ming-Hsi, Lin, Su-Chen, Hsiao, Chia-Hsin, Chao, Hsin-Ju, Yang, Hung-Ren, Liao, Chien-Chun, Chuang, Po-Wei, Wu, Huang-Pi, Huang, Chiung-Yi, Leng, Chih-Hsiang, Liu, Shih-Jen, Chen, Hsin-Wei, Chou, Ai-Hsiang, Hu, Alan Yung-Chih, Chong, Pele
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924384/
https://ncbi.nlm.nih.gov/pubmed/20808862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012279
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