MiR-145, a new regulator of the DNA Fragmentation Factor-45 (DFF45)-mediated apoptotic network

BACKGROUND: MicroRNA-145 (miR-145) is considered to play key roles in many cellular processes, such as proliferation, differentiation and apoptosis, by inhibiting target gene expression. DNA Fragmentation Factor-45 (DFF45) has been found to be the substrate of Caspase-3, and the cleavage of DFF45 by...

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Autores principales: Zhang, Jianjun, Guo, Haiyan, Qian, Guanxiang, Ge, Shengfang, Ji, Huifeng, Hu, Xiaobo, Chen, Wantao
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924312/
https://ncbi.nlm.nih.gov/pubmed/20687965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-211
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