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Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation
The protective antigen (PA) component of the anthrax toxin forms pores within the low pH environment of host endosomes, through mechanisms that are poorly understood. It has been proposed that pore formation is dependent on histidine protonation. In previous work, we biosynthetically incorporated 2-...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924283/ https://ncbi.nlm.nih.gov/pubmed/20672855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100647z |
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