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Nicotinic Receptor Subunit α5 Modifies Assembly, Up-regulation, and Response to Pro-inflammatory Cytokines

In the mammalian brain high affinity nicotine-binding sites are composed of at least the α4 and β2 subunits. Additional nicotinic acetylcholine receptor subunits that are often co-expressed with α4+β2 include α5. The introduction of α5 into 293 cells expressing α4+β2 strongly favors assembly of α4+α...

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Main Authors: Gahring, Lorise C., Rogers, Scott W.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924004/
https://ncbi.nlm.nih.gov/pubmed/20566638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105346
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