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The multi-functional role of insulin-like growth factor binding proteins in bone

The insulin-like growth factor (IGF) system is an important regulator of bone formation. The IGFs (IGF-I and IGF-II) are the most abundant growth factors produced by bone, and are regulated by their six high affinity binding proteins (IGFBPs). The IGFBPs are produced by osteoblasts and are responsib...

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Bibliographic Details
Main Authors: Govoni, Kristen E., Baylink, David J., Mohan, Subburaman
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923924/
https://ncbi.nlm.nih.gov/pubmed/15549410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-004-1658-y
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