Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias

BACKGROUND: Gene mutation is an important mechanism of myeloid leukemogenesis. However, the number and combination of gene mutated in myeloid malignancies is still a matter of investigation. METHODS: We searched for mutations in the ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 a...

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Hauptverfasser: Rocquain, Julien, Carbuccia, Nadine, Trouplin, Virginie, Raynaud, Stéphane, Murati, Anne, Nezri, Meyer, Tadrist, Zoulika, Olschwang, Sylviane, Vey, Norbert, Birnbaum, Daniel, Gelsi-Boyer, Véronique, Mozziconacci, Marie-Joelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923633/
https://ncbi.nlm.nih.gov/pubmed/20678218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-401
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