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Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases
The ASXL1 gene is one of the most frequently mutated genes in malignant myeloid diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic regulation of gene expression. ASXL1 mutations are found in myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), chronic...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355025/ https://ncbi.nlm.nih.gov/pubmed/22436456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-5-12 |
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