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Chronic Antigen Stimulation Alone Is Sufficient to Drive CD8(+) T Cell Exhaustion
The failure of CD8(+) T cells to respond to chronic infection has been termed “exhaustion” and describes the condition in which CD8(+) T cells exhibit reduced differentiation, proliferation, and effector function. CD8(+) T cell exhaustion has been extensively studied in the murine model of chronic i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923544/ https://ncbi.nlm.nih.gov/pubmed/19454664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800997 |
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