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RSK2 mediates NF-κB activity through the phosphorylation of IκBα in the TNF-R1 pathway
The ribosomal S6 kinase 2 (RSK2) is a well-known serine/threonine kinase and a member of the p90 ribosomal S6 kinase (p90RSK) family of proteins. It is activated downstream of the MEK/ERKs cascade by mitogenic stimuli such as EGF or TPA. Here, we show that RSK2 is activated by treatment with tumor n...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Federation of American Societies for Experimental Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923348/ https://ncbi.nlm.nih.gov/pubmed/20385620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-151290 |
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