Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

Degeneration of motor neurons contributes to senescence-associated loss of muscle function and underlies human neurodegenerative conditions such as amyotrophic lateral sclerosis and spinal muscular atrophy. The identification of genetic factors contributing to motor neuron vulnerability and degenera...

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Detalhes bibliográficos
Main Authors: de Waard, Monique C., van der Pluijm, Ingrid, Zuiderveen Borgesius, Nils, Comley, Laura H., Haasdijk, Elize D., Rijksen, Yvonne, Ridwan, Yanto, Zondag, Gerben, Hoeijmakers, Jan H. J., Elgersma, Ype, Gillingwater, Thomas H., Jaarsma, Dick
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923326/
https://ncbi.nlm.nih.gov/pubmed/20602234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0715-9
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