Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites

Motivation: Histone acetylation (HAc) is associated with open chromatin, and HAc has been shown to facilitate transcription factor (TF) binding in mammalian cells. In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages....

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Detalhes bibliográficos
Main Authors: Ramsey, Stephen A., Knijnenburg, Theo A., Kennedy, Kathleen A., Zak, Daniel E., Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Lampano, Aaron E., Litvak, Vladimir, Navarro, Garnet, Stolyar, Tetyana, Aderem, Alan, Shmulevich, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Discovery Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922897/
https://ncbi.nlm.nih.gov/pubmed/20663846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq405
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