Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites

Motivation: Histone acetylation (HAc) is associated with open chromatin, and HAc has been shown to facilitate transcription factor (TF) binding in mammalian cells. In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages....

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Bibliografiska uppgifter
Huvudupphovsmän: Ramsey, Stephen A., Knijnenburg, Theo A., Kennedy, Kathleen A., Zak, Daniel E., Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Lampano, Aaron E., Litvak, Vladimir, Navarro, Garnet, Stolyar, Tetyana, Aderem, Alan, Shmulevich, Ilya
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Discovery Note
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922897/
https://ncbi.nlm.nih.gov/pubmed/20663846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq405
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