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Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites

Motivation: Histone acetylation (HAc) is associated with open chromatin, and HAc has been shown to facilitate transcription factor (TF) binding in mammalian cells. In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages....

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Bibliografische gegevens
Hoofdauteurs: Ramsey, Stephen A., Knijnenburg, Theo A., Kennedy, Kathleen A., Zak, Daniel E., Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Lampano, Aaron E., Litvak, Vladimir, Navarro, Garnet, Stolyar, Tetyana, Aderem, Alan, Shmulevich, Ilya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922897/
https://ncbi.nlm.nih.gov/pubmed/20663846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq405
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