Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites

Motivation: Histone acetylation (HAc) is associated with open chromatin, and HAc has been shown to facilitate transcription factor (TF) binding in mammalian cells. In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages....

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Autors principals: Ramsey, Stephen A., Knijnenburg, Theo A., Kennedy, Kathleen A., Zak, Daniel E., Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Lampano, Aaron E., Litvak, Vladimir, Navarro, Garnet, Stolyar, Tetyana, Aderem, Alan, Shmulevich, Ilya
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Discovery Note
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922897/
https://ncbi.nlm.nih.gov/pubmed/20663846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq405
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