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Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites
Motivation: Histone acetylation (HAc) is associated with open chromatin, and HAc has been shown to facilitate transcription factor (TF) binding in mammalian cells. In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages....
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922897/ https://ncbi.nlm.nih.gov/pubmed/20663846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq405 |
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