Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites

Motivation: Histone acetylation (HAc) is associated with open chromatin, and HAc has been shown to facilitate transcription factor (TF) binding in mammalian cells. In the innate immune system context, epigenetic studies strongly implicate HAc in the transcriptional response of activated macrophages....

Full description

Saved in:
Bibliographic Details
Main Authors: Ramsey, Stephen A., Knijnenburg, Theo A., Kennedy, Kathleen A., Zak, Daniel E., Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Lampano, Aaron E., Litvak, Vladimir, Navarro, Garnet, Stolyar, Tetyana, Aderem, Alan, Shmulevich, Ilya
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Discovery Note
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922897/
https://ncbi.nlm.nih.gov/pubmed/20663846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq405
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items