Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics

Macrophages are versatile immune cells that can detect a variety of pathogen-associated molecular patterns through their Toll-like receptors (TLRs). In response to microbial challenge, the TLR-stimulated macrophage undergoes an activation program controlled by a dynamically inducible transcriptional...

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Main Authors: Ramsey, Stephen A., Klemm, Sandy L., Zak, Daniel E., Kennedy, Kathleen A., Thorsson, Vesteinn, Li, Bin, Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Litvak, Vladimir, Navarro, Garnet, Roach, Jared C., Rosenberger, Carrie M., Rust, Alistair G., Yudkovsky, Natalya, Aderem, Alan, Shmulevich, Ilya
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265556/
https://ncbi.nlm.nih.gov/pubmed/18369420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000021
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