Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics

Macrophages are versatile immune cells that can detect a variety of pathogen-associated molecular patterns through their Toll-like receptors (TLRs). In response to microbial challenge, the TLR-stimulated macrophage undergoes an activation program controlled by a dynamically inducible transcriptional...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ramsey, Stephen A., Klemm, Sandy L., Zak, Daniel E., Kennedy, Kathleen A., Thorsson, Vesteinn, Li, Bin, Gilchrist, Mark, Gold, Elizabeth S., Johnson, Carrie D., Litvak, Vladimir, Navarro, Garnet, Roach, Jared C., Rosenberger, Carrie M., Rust, Alistair G., Yudkovsky, Natalya, Aderem, Alan, Shmulevich, Ilya
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2008
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265556/
https://ncbi.nlm.nih.gov/pubmed/18369420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000021
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