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Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIP(L)
Cellular FADD-like interleukin-1β–converting enzyme inhibitory proteins (c-FLIPs; isoforms c-FLIP long [c-FLIP(L)], c-FLIP short [c-FLIP(S)], and c-FLIP Raji [c-FLIP(R)]) regulate caspase-8 activation and death receptor (DR)–induced apoptosis. In this study, using a combination of mathematical model...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922645/ https://ncbi.nlm.nih.gov/pubmed/20696707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002060 |
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