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Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism
EphA2, a member of the Eph receptor family, is frequently overexpressed in a variety of human cancers, including breast cancers, and promotes cancer cell motility and invasion independently of its ligand ephrin stimulation. In this study, we identify Ephexin4 as a guanine nucleotide exchange factor...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922637/ https://ncbi.nlm.nih.gov/pubmed/20679435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201005141 |
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