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Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

EphA2, a member of the Eph receptor family, is frequently overexpressed in a variety of human cancers, including breast cancers, and promotes cancer cell motility and invasion independently of its ligand ephrin stimulation. In this study, we identify Ephexin4 as a guanine nucleotide exchange factor...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hiramoto-Yamaki, Nao, Takeuchi, Shingo, Ueda, Shuhei, Harada, Kohei, Fujimoto, Satoshi, Negishi, Manabu, Katoh, Hironori
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922637/
https://ncbi.nlm.nih.gov/pubmed/20679435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201005141
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