eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

Translational regulation plays a critical role in the control of cell growth and proliferation. A key player in translational control is eIF4E, the mRNA 5′ cap-binding protein. Aberrant expression of eIF4E promotes tumorigenesis and has been implicated in cancer development and progression. The acti...

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Hlavní autoři: Furic, Luc, Rong, Liwei, Larsson, Ola, Koumakpayi, Ismaël Hervé, Yoshida, Kaori, Brueschke, Andrea, Petroulakis, Emmanuel, Robichaud, Nathaniel, Pollak, Michael, Gaboury, Louis A., Pandolfi, Pier Paolo, Saad, Fred, Sonenberg, Nahum
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922605/
https://ncbi.nlm.nih.gov/pubmed/20679199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005320107
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