Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

The progression of cancers from primary tumors to invasive and metastatic stages accounts for the overwhelming majority of cancer deaths. Understanding the molecular events which promote metastasis is thus critical in the clinic. Translational control is emerging as an important factor in tumorigene...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Robichaud, Nathaniel, del Rincon, Sonia V., Huor, Bonnie, Alain, Tommy, Petruccelli, Andy, Hearnden, Jaclyn, Goncalves, Christophe, Grotegut, Stefan, Spruck, Charles H., Furic, Luc, Larsson, Ola, Miller, Wilson H., Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978545/
https://ncbi.nlm.nih.gov/pubmed/24909168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.146
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