CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy

Tumor growth requires neoangiogenesis. VEGF is the most potent proangiogenic factor. Dysregulation of hypoxia-inducible factor (HIF) or cytokine stimuli such as those involving the chemokine receptor 4/stromal-derived cell factor 1 (CXCR4/SDF-1) axis are the major cause of ectopic overexpression of...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: de Nigris, Filomena, Crudele, Valeria, Giovane, Alfonso, Casamassimi, Amelia, Giordano, Antonio, Garban, Hermes J., Cacciatore, Francesco, Pentimalli, Francesca, Marquez-Garban, Diana C., Petrillo, Antonella, Cito, Letizia, Sommese, Linda, Fiore, Andrea, Petrillo, Mario, Siani, Alfredo, Barbieri, Antonio, Arra, Claudio, Rengo, Franco, Hayashi, Toshio, Al-Omran, Mohammed, Ignarro, Louis J., Napoli, Claudio
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2010
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922579/
https://ncbi.nlm.nih.gov/pubmed/20660740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008256107
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