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Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

Osteocytes with long dendritic processes are known to sense mechanical loading, which is essential for bone remodeling. There has been a long-standing debate with regard to which part(s) of osteocyte, the cell body versus the dendritic process, acts as a mechanical sensor. To address this question e...

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Autors principals: Burra, Sirisha, Nicolella, Daniel P., Francis, W. Loren, Freitas, Christopher J., Mueschke, Nicholas J., Poole, Kristin, Jiang, Jean X.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922284/
https://ncbi.nlm.nih.gov/pubmed/20643964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009382107
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