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Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
Due to its common dysregulation in epithelial-based cancers and extensive characterization of its role in tumor growth, epidermal growth factor receptor (EGFR) is a highly validated target for anticancer therapies. There has been particular interest in the development of monoclonal antibodies (mAbs)...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922117/ https://ncbi.nlm.nih.gov/pubmed/20616078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913476107 |
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