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Polar groups in membrane channels: Consequences of replacing alanines with serines in membrane-spanning gramicidin channels
To explore the consequences of burying polar, hydrogen-bonding hydroxyl groups within the hydrocarbon core of lipid bilayer membranes, we examined the structural and functional effects of alanine-to-serine substitutions in bilayer-spanning gramicidin channels. A native Ala was replaced by Ser at pos...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921912/ https://ncbi.nlm.nih.gov/pubmed/20695525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100857g |
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