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The Membrane Interface dictates Different Anchor Roles for “Inner Pair” and “Outer Pair” Tryptophan Indole Rings in Gramicidin A Channels
We investigated the effects of substituting two of the four tryptophans (the “inner pair” Trp(9,11) or the “outer pair” Trp(13,15)) in gramicidin A (gA) channels. The conformational preferences of the double-substituted gA analogues were assessed using circular dichroism spectroscopy and size-exclus...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115663/ https://ncbi.nlm.nih.gov/pubmed/21539360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200136e |
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