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Thermodynamic Analysis of a Molecular Chaperone Binding to Unfolded Protein Substrates

Molecular chaperones are a highly diverse group of proteins that recognize and bind unfolded proteins in order to facilitate protein folding and prevent non-specific protein aggregation. The mechanisms by which chaperones bind their protein substrates have been studied for decades. However, there ar...

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Autors principals: Xu, Ying, Schmitt, Sebastian, Tang, Liangjie, Jakob, Ursula, Fitzgerald, Michael C.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921697/
https://ncbi.nlm.nih.gov/pubmed/20073505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902010t
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