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Anatomically dissociable effects of dopamine D1 receptor agonists on reward and relief of withdrawal in morphine-dependent rats
RATIONALE: Chronic opiate administration induces neuro-adaptations within the nucleus accumbens (NAc) and ventral tegmental area (VTA) that can contribute to dependence. We have shown that morphine dependence shifts the behavioral consequences of D1 dopamine (DA) receptor signaling: systemic adminis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921644/ https://ncbi.nlm.nih.gov/pubmed/19148621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1454-7 |
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