A Minor Catalytic Activity of Src Family Kinases Is Sufficient for Maximal Activation of Mast Cells via the High-Affinity IgE Receptor

Src family kinases (SFK) are critical for initiating and regulating the response of mast cells activated by engagement of the high-affinity IgE receptor, FcεRI. Lyn is the predominant SFK in mast cells and has been ascribed both positive and negative roles in regulating mast cell activation. We anal...

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Detalhes bibliográficos
Main Authors: Poderycki, Michael, Tomimori, Yoshiaki, Ando, Tomoaki, Xiao, Wenbin, Maeda-Yamamoto, Mari, Sauer, Karsten, Kawakami, Yuko, Kawakami, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921446/
https://ncbi.nlm.nih.gov/pubmed/19949072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901590
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