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The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn
IgE/antigen-dependent mast cell activation plays a central role in immediate hypersensitivity and other allergic reactions. The Src family tyrosine kinase (SFK) Lyn is activated by the cross-linking of high-affinity IgE receptors (FcϵRI). Activated Lyn phosphorylates the FcϵRI subunits, β and γ, lea...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1988937/ https://ncbi.nlm.nih.gov/pubmed/17513616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-066092 |
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