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Effect of increased HoxB4 on human megakaryocytic development
In order to ex vivo produce clinically useful quantity of platelets, we may need to firstly enhance early self-renewal of hematopoietic stem cells (HSCs) and/or megakaryocyte (Mk) progenitors. The homeodomain transcription factor HoxB4 has been shown to be an important regulator of stem cell renewal...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921174/ https://ncbi.nlm.nih.gov/pubmed/20599537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.06.075 |
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