Cooperative DNA binding of the human HoxB5 (Hox-2.1) protein is under redox regulation in vitro.

The human HoxB5 (Hox-2.1) gene product is a sequence-specific DNA binding protein. Cooperative interactions stabilize in vitro DNA binding of the HoxB5 protein to tandem binding sites by at least 100-fold relative to binding to a single site. The HoxB5 homeodomain is sufficient for sequence-specific...

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Bibliographic Details
Main Authors: Galang, C K, Hauser, C A
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC360087/
https://ncbi.nlm.nih.gov/pubmed/8101633
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