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Cooperative DNA binding of the human HoxB5 (Hox-2.1) protein is under redox regulation in vitro.

The human HoxB5 (Hox-2.1) gene product is a sequence-specific DNA binding protein. Cooperative interactions stabilize in vitro DNA binding of the HoxB5 protein to tandem binding sites by at least 100-fold relative to binding to a single site. The HoxB5 homeodomain is sufficient for sequence-specific...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Galang, C K, Hauser, C A
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360087/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8101633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4609-4617.1993
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