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Effect of increased HoxB4 on human megakaryocytic development

In order to ex vivo produce clinically useful quantity of platelets, we may need to firstly enhance early self-renewal of hematopoietic stem cells (HSCs) and/or megakaryocyte (Mk) progenitors. The homeodomain transcription factor HoxB4 has been shown to be an important regulator of stem cell renewal...

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Sonraí Bibleagrafaíochta
Main Authors: Zhong, Yiming, Sullenbarger, Brent, Lasky, Larry C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921174/
https://ncbi.nlm.nih.gov/pubmed/20599537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.06.075
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