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Preparation of the Caspase-3/-7 substrate Ac-DEVD-pNA via Solution-Phase Peptide Synthesis

The caspase enzymes are integral to cellular inflammation and apoptotic cascades, and are commonly studied by cell biologists, medicinal chemists, and chemical biologists. In particular, the assessment of caspase enzymatic activity is a standard method to evaluate cell death pathways and novel apopt...

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Detalhes bibliográficos
Main Authors: Peterson, Quinn P., Goode, David R., West, Diana C., Botham, Rachel C., Hergenrother, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921128/
https://ncbi.nlm.nih.gov/pubmed/20134429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.223
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