The caspase-3 inhibitor (peptide Z-DEVD-FMK) affects the survival and function of platelets in platelet concentrate during storage

BACKGROUND: Although apoptosis occurs in nucleated cells, studies show that this event also occurs in some anucleated cells such as platelets. During storage of platelets, the viability of platelets decreased, storage lesions were observed, and cells underwent apoptosis. We investigated the effects...

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Autori principali: Shiri, Reza, Yari, Fatemeh, Ahmadinejad, Minoo, Vaeli, Shahram, Tabatabaei, Mohammad Reza
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974957/
https://ncbi.nlm.nih.gov/pubmed/24724067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2014.49.1.49
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