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The Impact of Mineralocorticoid Receptor ISO/VAL Genotype (rs5522) and Stress on Reward Learning

Research suggests that stress disrupts reinforcement learning and induces anhedonia. The mineralocorticoid receptor (MR) determines the sensitivity of the stress response and the missense iso/val polymorphism (Ile180Val, rs5522) of the MR gene (NR3C2) has been associated with enhanced physiological...

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Detalhes bibliográficos
Main Authors: Bogdan, Ryan, Perlis, Roy H., Fagerness, Jesen, Pizzagalli, Diego A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921022/
https://ncbi.nlm.nih.gov/pubmed/20528958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2010.00600.x
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