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Variation in TREK1 gene linked to depression‐resistant phenotype is associated with potentiated neural responses to rewards in humans

The TREK1 gene has been linked to a depression‐resistant phenotype in rodents and antidepressant response in humans, but the neural mechanisms underlying these links are unclear. Because TREK1 is expressed in reward‐related basal ganglia regions, it has been hypothesized that TREK1 genetic variation...

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Detalhes bibliográficos
Main Authors: Dillon, Daniel G., Bogdan, Ryan, Fagerness, Jesen, Holmes, Avram J., Perlis, Roy H., Pizzagalli, Diego A.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885957/
https://ncbi.nlm.nih.gov/pubmed/19621370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.20858
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