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Constitutive overexpression of BAFF in autoimmune-resistant hosts drives only some aspects of systemic lupus erythematosus-like autoimmunity
OBJECTIVE: To determine whether overexpression of BAFF can promote SLE-like autoimmunity in hosts that otherwise are autoimmune-resistant. METHODS: We utilized MHC II-deficient C57BL/6 (B6) mice as a model of resistance to SLE and Sles1-bearing B6 mice as a model of resistance to the autoantibody-pr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921019/ https://ncbi.nlm.nih.gov/pubmed/20506216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27502 |
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