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Mouse TRIP13/PCH2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during Meiosis

Accurate chromosome segregation during meiosis requires that homologous chromosomes pair and become physically connected so that they can orient properly on the meiosis I spindle. These connections are formed by homologous recombination closely integrated with the development of meiosis-specific, hi...

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Bibliographic Details
Main Authors: Roig, Ignasi, Dowdle, James A., Toth, Attila, de Rooij, Dirk G., Jasin, Maria, Keeney, Scott
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920839/
https://ncbi.nlm.nih.gov/pubmed/20711356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001062
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