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Motor-Coordination-Dependent Learning, More than Others, Is Impaired in Transgenic Mice Expressing Pseudorabies Virus Immediate-Early Protein IE180

The cerebellum in transgenic mice expressing pseudorabies virus immediate-early protein IE180 (TgIE96) was substantially diminished in size, and its histoarchitecture was severely disorganized, resulting in severe ataxia. TgIE96 mice can therefore be used as an experimental model to study the involv...

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Autors principals: López-Ramos, Juan C., Tomioka, Yukiko, Morimatsu, Masami, Yamamoto, Sayo, Ozaki, Kinuyo, Ono, Etsuro, Delgado-García, José M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920824/
https://ncbi.nlm.nih.gov/pubmed/20711341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012123
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