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Characterization of a Replication-Incompetent Pseudorabies Virus Mutant Lacking the Sole Immediate Early Gene IE180

The alphaherpesvirus pseudorabies virus (PRV) encodes a single immediate early gene called IE180. The IE180 protein is a potent transcriptional activator of viral genes involved in DNA replication and RNA transcription. A PRV mutant with both copies of IE180 deleted was constructed 20 years ago (S....

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Wu, Brendan W., Engel, Esteban A., Enquist, Lynn W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235210/
https://ncbi.nlm.nih.gov/pubmed/25389174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01850-14
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