A soluble form of human nectin-2 impairs exocrine secretion of pancreas and formation of zymogen granules in transgenic mice

Transgenic mouse lines expressing a soluble form of human nectin-2 (hNectin-2Ig Tg) exhibited distinctive elevation of amylase and lipase levels in the sera. In this study, we aimed to clarify the histopathology and to propose the transgenic mouse lines as new animal model for characteristic pancrea...

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Vydáno v:Biochem Biophys Rep
Hlavní autoři: Tomioka, Yukiko, Fujimoto, Yoshikazu, Nakai, Kanji, Ozaki, Kinuyo, Yamamoto, Sayo, Suyama, Haruka, Morimatsu, Masami, Ito, Toshihiro, Ono, Etsuro
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600445/
https://ncbi.nlm.nih.gov/pubmed/28955824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.12.006
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