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A soluble form of human nectin-2 impairs exocrine secretion of pancreas and formation of zymogen granules in transgenic mice

Transgenic mouse lines expressing a soluble form of human nectin-2 (hNectin-2Ig Tg) exhibited distinctive elevation of amylase and lipase levels in the sera. In this study, we aimed to clarify the histopathology and to propose the transgenic mouse lines as new animal model for characteristic pancrea...

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Detaylı Bibliyografya
Yayımlandı:Biochem Biophys Rep
Asıl Yazarlar: Tomioka, Yukiko, Fujimoto, Yoshikazu, Nakai, Kanji, Ozaki, Kinuyo, Yamamoto, Sayo, Suyama, Haruka, Morimatsu, Masami, Ito, Toshihiro, Ono, Etsuro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600445/
https://ncbi.nlm.nih.gov/pubmed/28955824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.12.006
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