A soluble form of human nectin-2 impairs exocrine secretion of pancreas and formation of zymogen granules in transgenic mice

Transgenic mouse lines expressing a soluble form of human nectin-2 (hNectin-2Ig Tg) exhibited distinctive elevation of amylase and lipase levels in the sera. In this study, we aimed to clarify the histopathology and to propose the transgenic mouse lines as new animal model for characteristic pancrea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Biophys Rep
Prif Awduron: Tomioka, Yukiko, Fujimoto, Yoshikazu, Nakai, Kanji, Ozaki, Kinuyo, Yamamoto, Sayo, Suyama, Haruka, Morimatsu, Masami, Ito, Toshihiro, Ono, Etsuro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600445/
https://ncbi.nlm.nih.gov/pubmed/28955824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.12.006
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