A soluble form of human nectin-2 impairs exocrine secretion of pancreas and formation of zymogen granules in transgenic mice

Transgenic mouse lines expressing a soluble form of human nectin-2 (hNectin-2Ig Tg) exhibited distinctive elevation of amylase and lipase levels in the sera. In this study, we aimed to clarify the histopathology and to propose the transgenic mouse lines as new animal model for characteristic pancrea...

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Bibliografiska uppgifter
I publikationen:Biochem Biophys Rep
Huvudupphovsmän: Tomioka, Yukiko, Fujimoto, Yoshikazu, Nakai, Kanji, Ozaki, Kinuyo, Yamamoto, Sayo, Suyama, Haruka, Morimatsu, Masami, Ito, Toshihiro, Ono, Etsuro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600445/
https://ncbi.nlm.nih.gov/pubmed/28955824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.12.006
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