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Positive Feedback Regulation between Phospholipase D and Wnt Signaling Promotes Wnt-Driven Anchorage-Independent Growth of Colorectal Cancer Cells

BACKGROUND: Aberrant activation of the canonical Wnt/β-catenin pathway occurs in almost all colorectal cancers and contributes to their growth, invasion and survival. Phopholipase D (PLD) has been implicated in progression of colorectal carcinoma However, an understanding of the targets and regulati...

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מידע ביבליוגרפי
Main Authors: Kang, Dong Woo, Min, Do Sik
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920823/
https://ncbi.nlm.nih.gov/pubmed/20711340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012109
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