Bending the Rules of Transcriptional Repression: Tightly Looped DNA Directly Represses T7 RNA Polymerase

From supercoiled DNA to the tight loops of DNA formed by some gene repressors, DNA in cells is often highly bent. Despite evidence that transcription by RNA polymerase (RNAP) is affected in systems where DNA is deformed significantly, the mechanistic details underlying the relationship between polym...

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Bibliografiske detaljer
Main Authors: Lionberger, Troy A., Meyhöfer, Edgar
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2010
Fag:
Muscle, Molecular Motors, and Cell Motility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920717/
https://ncbi.nlm.nih.gov/pubmed/20712997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.074
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