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Bending the Rules of Transcriptional Repression: Tightly Looped DNA Directly Represses T7 RNA Polymerase

From supercoiled DNA to the tight loops of DNA formed by some gene repressors, DNA in cells is often highly bent. Despite evidence that transcription by RNA polymerase (RNAP) is affected in systems where DNA is deformed significantly, the mechanistic details underlying the relationship between polym...

詳細記述

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書誌詳細
主要な著者: Lionberger, Troy A., Meyhöfer, Edgar
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920717/
https://ncbi.nlm.nih.gov/pubmed/20712997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.074
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