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A Small Post-Translocation Energy Bias Aids Nucleotide Selection in T7 RNA Polymerase Transcription
The RNA polymerase (RNAP) of bacteriophage T7 is a single subunit enzyme that can transcribe DNA to RNA in the absence of additional protein factors. In this work, we present a model of T7 RNAP translocation during elongation. Based on structural information and experimental data from single-molecul...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274829/ https://ncbi.nlm.nih.gov/pubmed/22325276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.028 |
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