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A Small Post-Translocation Energy Bias Aids Nucleotide Selection in T7 RNA Polymerase Transcription

The RNA polymerase (RNAP) of bacteriophage T7 is a single subunit enzyme that can transcribe DNA to RNA in the absence of additional protein factors. In this work, we present a model of T7 RNAP translocation during elongation. Based on structural information and experimental data from single-molecul...

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Detalhes bibliográficos
Main Authors: Yu, Jin, Oster, George
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274829/
https://ncbi.nlm.nih.gov/pubmed/22325276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.12.028
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