Prostatic Acid Phosphatase Reduces Thermal Sensitivity and Chronic Pain Sensitization by Depleting Phosphatidylinositol 4,5-Bisphosphate

Prostatic acid phosphatase (PAP) is expressed in nociceptive dorsal root ganglion (DRG) neurons, functions as an ectonucleotidase, and generates adenosine extracellularly. Here, we found that PAP inhibits noxious thermal sensitivity and sensitization that is associated with chronic pain through sust...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Sowa, Nathaniel A., Street, Sarah E., Vihko, Pirkko, Zylka, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2010
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920622/
https://ncbi.nlm.nih.gov/pubmed/20685973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2162-10.2010
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares