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P2Y nucleotide receptors: Promise of therapeutic applications

Extracellular nucleotides, such as ATP and UTP, have distinct signaling roles through a class of G protein-coupled receptors, termed P2Y. However, the receptor ligands are typically charged molecules of low bioavailability and stability in vivo. Recent progress in the development of selective agonis...

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Autors principals: Jacobson, Kenneth A., Boeynaems, Jean-Marie
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920619/
https://ncbi.nlm.nih.gov/pubmed/20594935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2010.05.011
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